nov., a medium-sized proteolytic spirochaete isolated from lesions of human periodontitis and acute necrotizing ulcerative gingivitisSynergistic biofilm formation by Treponema denticola and Porphyromonas gingivalisGenetic heterogeneity among strains of Treponema phagedenis-like spirochetes isolated from dairy cattle with papillomatous digital dermatitis in JapanInterbacterial binding among strains of pathogenic and commensal oral bacterial speciesStimulation of growth of Porphyromonas gingivalis by cell extracts from Tannerella forsythiaFormation of methyl mercaptan from L-methionine by Porphyromonas gingivalisInternational & American Associations for Dental Research

By continuing to browse this site, you agree to its use of cookies as described in our I have read and accept the Wiley Online Library Terms and Conditions of Use Background/aims: Treponema denticola outer membrane proteins are postulated to have key roles in microbe-host interactions in periodontitis. Use the link below to share a full-text version of this article with your friends and colleagues. This product could help youAccessing resources off campus can be a challenge. This review focuses on emerging knowledge of virulence mechanisms of Treponema denticola as well as mechanisms of other less-studied oral treponemes. Dashper, C.A.

If you do not receive an email within 10 minutes, your email address may not be registered, Seers. Members of _ can log in with their society credentials belowIADR members have access to this journal as part of their membership. Dashper, C.A. and you may need to create a new Wiley Online Library account.Enter your email address below and we will send you your usernameIf the address matches an existing account you will receive an email with instructions to retrieve your username The aim of this study was to establish a link between periodontal disease and Alzheimer's disease (AD) with a view to identifying the major periodontal disease bacteria (Treponema denticola, Tannerella forsythia, and Porphyromonas gingivalis) and/or bacterial components in brain tissue from 12 h postmortem delay.

ReynoldsCooperative Research Centre for Oral Health, Melbourne Dental School and Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia  Cooperative Research Centre for Oral Health, Melbourne Dental School and Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia  Cooperative Research Centre for Oral Health, Melbourne Dental School and Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia  Cooperative Research Centre for Oral Health, Melbourne Dental School and Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia   Cooperative Research Centre for Oral Health, Melbourne Dental School and Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia  Cooperative Research Centre for Oral Health, Melbourne Dental School and Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia  Cooperative Research Centre for Oral Health, Melbourne Dental School and Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia  Cooperative Research Centre for Oral Health, Melbourne Dental School and Bio21 Institute, The University of Melbourne, 720 Swanston Street, Victoria, 3010, Australia   Members of _ can log in with their society credentials belowIADR members have access to this journal as part of their membership.

the site you are agreeing to our use of cookies.

One exception is the IgA1 protease that is considered to be an important virulence factor in S. pneumoniae (Janoff et al., 2013). By continuing to browse There are interesting parallels with other chronic diseases caused by treponemes that may indicate similar virulence characteristics. Virulence Factors of the Oral Spirochete Treponema denticola S.G. Dashper , C.A.

Learn more. in the large intestine of pigs by PCR amplification of the 16S rRNA geneShort-chain carboxylic-acid-stimulated, PMN-mediated gingival inflammationStimulation of in vitro growth of Treponema denticola by extracellular growth factors produced by Porphyromonas gingivalisAssociation of Treponema spp. Sign in using your membership username and password.S.G.

and intrageneric coaggregation among Fusobacterium sppBacterial outer membrane vesicles and the host-pathogen interactionInterspecies interactions within oral microbial communitiesVolatile fatty acids, metabolic by-products of periodontopathic bacteria, inhibit lymphocyte proliferation and cytokine productionLife below the gum line: pathogenic mechanisms of Porphyromonas gingivalisExposure of periodontal ligament cells to methyl mercaptan reduces intracellular pH and inhibits cell migrationImmune response and alveolar bone resorption in a mouse model of Treponema denticola infectionUpregulation of intercellular adhesion molecule 1 and proinflammatory cytokines by the major surface proteins of Treponema maltophilum and Treponema lecithinolyticum, the phylogenetic group IV oral spirochetes associated with periodontitis and endodontic infectionsThe major outer membrane protein of a periodontopathogen induces IFN-B and IFN-stimulated genes in monocytes via lipid raft and TANK-binding kinase 1/IFN regulatory factor 3Expression of Treponema denticola oligopeptidase B in Escherichia coliCleavage of Treponema denticola PrcA polypeptide to yield protease complex-associated proteins Prca1 and Prca2 is dependent on PrtPGene inactivation in the oral spirochete Treponema denticola: construction of an flgE mutantCharacterization of a novel methyl-accepting chemotaxis gene, dmcB, from the oral spirochete Treponema denticolaA major autolysin of Pseudomonas aeruginosa: subcellular distribution, potential role in cell growth and division and secretion in surface membrane vesiclesMotility and chemotaxis in tissue penetration of oral epithelial cell layers by Treponema denticolaConstruction and characterization of a cheA mutant of Treponema denticolaThe major outer sheath protein of Treponema denticola selectively inhibits Rac1 activation in murine neutrophilsComprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotesGamma-glutamyltransferase from the outer cell envelope of Treponema denticola ATCC 35405Role of the chymotrypsin-like membrane-associated proteinase from Treponema denticola ATCC 35405 in inactivation of bioactive peptidesMembrane vesicles traffic signals and facilitate group activities in a prokaryoteIdentification of the gene encoding the FhbB protein of Treponema denticola, a highly unique factor H-like protein 1 binding proteinAnalysis of a unique interaction between the complement regulatory protein factor H and the periodontal pathogen Treponema denticolaSite-specific development of periodontal disease is associated with increased levels of Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia in subgingival plaqueTreponema denticola biofilm-induced expression of a bacteriophage, toxin-antitoxin systems and transposasesThe Treponema denticola surface protease dentilisin degrades interleukin-1 beta (IL-1 beta), IL-6, and tumor necrosis factor alphaIdentification of a novel, invasive, not-yet-cultivated Treponema sp.